Real-Time Open Reports

Feb 2, 2021: Huntingtin “coats” mitotic chromosomes when PAR break-down is inhibited

Dec 2, 2019: Experiments on PAR levels in HD cells and huntingtin PAR binding

Sept 24, 2019: Update on the huntingtin PAR binding story

July 15, 2019: Huntingtin chromatin retention in PARP KO cells

July 9, 2019: Detecting poly ADP ribose

June 27, 2019: The Year in Review

April 1, 2019: Why the heck does huntingtin bind PAR?

March 5, 2019: Could cancer drugs help with HD?

October 18, 2018: Hypothesis: Poly ADP ribose signaling is dysregulated in Huntington’s disease

September 7, 2018: Is huntingtin a PAR-binding protein?

July 23, 2018: A closer look at the hits generates 2 new hypotheses

April 14, 2018: Next steps in the identification of ROS-related huntingtin protein-protein interactions

January 29, 2018: ROS-dependent huntingtin interactions in mouse striatal cells

January 8, 2018: Update: Measuring DNA repair capacity and visualizing huntingtin in HD patient cells

October 31, 2017: Visualizing real huntingtin protein in cells from an HD patient

September 19, 2017: Measuring the rate of DNA repair in HD cells

August 21, 2017: Pulling huntingtin-associated DNA repair proteins out of HD patient cells

August 5, 2017: Testing oxidative stress conditions for huntingtin-DNA repair protein interactions

July 21, 2017: Real Time Report: The Oxidative Stress Interactome Project