Update: Measuring DNA repair capacity and visualizing huntingtin in HD patient cells

Blog post by Dr. Tamara Maiuri Image credit: Justinas Previously I described a method to measure DNA repair capacity in cells: the GFP reactivation assay. This worked nicely in mouse striatal cells, with HD cells consistently showing about half the repair capacity of wild type cells. I have since┬átried it in cells from HD patients, … Continue reading Update: Measuring DNA repair capacity and visualizing huntingtin in HD patient cells