Pulling huntingtin-associated DNA repair proteins out of HD patient cells

Blog post by Dr. Tamara Maiuri Now that the cross-linking, fractionation, and oxidative stress conditions have been worked out to pull huntingtin and its interactors out of the “easy-to-work-with” HEK293 cells, it’s time to try out the system in HD patient fibroblasts. These cells come from real HD patients and controls such as a sibling … Continue reading Pulling huntingtin-associated DNA repair proteins out of HD patient cells